sitelogo
 Home»Biochemistry» Evaluation of the immunomodulatory effect of oral administration of the methanol extract of gongronema latifolium (utazi) in wistar albino rats

Evaluation of the immunomodulatory effect of oral administration of the methanol extract of gongronema latifolium (utazi) in wistar albino rats

 Department: Biochemistry  
 By: usericon rashford  

 Project ID: 621
   Rating:  (2.9) votes: 18
Rate this project
   Price:₦3000
Abstract
The aim of the present study was to evaluate the immunomodulatory effect of methanol  extract of Gongronema latifolium (utazi) on Wistar Albino Rats. A total of sixteen (16) Wistar albino rats were used for the study and divided into four (4) groups of four (4) rats each. The normal control was administered normal saline while the negative control was administered pyrogallol in order to suppress the immune system. The treated rats were administered 200 mg/kg body weight and 400 mg/kg body weight of the plant extract and 2% pyrogallol to represent the low and high doses respectively. These administrations lasted 21 days after which blood was drawn through ocular puncture and serum collected for the assay. The immunomodulatory activity was evaluated on haematological indices (packed cell volume, haemoglobin and total white blood cell count), haemaglutination titre (primary and secondary humoral antibody) and the delayed type hypersensitivity (DTH). No significant (p0.05) differences were observed in the haematological indices. Significant (P0.05) increase. These comparison were made against the negative control. This study suggests that Gongronema latifolium possesses immunomodulatory effect....
Preview +
Other Biochemistry project topics and materials you might be interested in
»Phytochemical and nutritive composition of fluted pumpkin
»Determination of ascorbic acid in selected fruits mango, orange and pineapple using spectro-photometric method
»Comparative evaluation of heavy metal loads in some selected soft drinks in Owerri, Imo state
»Antilipidemic effect of water (H2O) extract of desmodium velutinum leaves on albino Wistar rats
»The effect of water extract of cola nitida pod on lipoprotein concentrations of albino Wistar rats
»Preliminary investigation on effects of burantashi extract on lipoproteins of albino male and female whistar rats
»The extraction of manganese (iv) ion from aqueous media using 1-phethyl-3-methyl pyrazolone-5
»Nutritive value, anti-nutrient and mineral composition of cashew nut (Anacardium Occidentale)
»Evaluation of the immunomodulatory effect of oral administration of the methanol extract of gongronema latifolium (utazi) in wistar albino rats
»Comparative study on the free radical scavenging potential of turmeric and beetroot
»Phytochemicals and minerals analysis of rosary pea (Abrus Precatorious leaves)
»Determination of total petroleum hydrocarbons in Niger river
»Qualitative phytochemical and gas chromatography mass spectrometry GCMS of Nhexane extracted leaves of sabicea calycina
»Hydrogen peroxide scavenging activities and reducing power of various fruits juice in Yenagoa
»Charges in the concentration of nitric oxide in the serum gills brain liver and kidney of clarias gariepinus exposed to glyphosatebased herbicide

Upload Project

Do you have project materials to share? Upload and earn with it.

Departments