The effect of crude avocado and pawpaw leaves extract on kidney function of guinea pigs Department: Microbiology By: francis05 Project ID: 2978 Rating: (3.2) votes: 11Rate this project12345 Price:₦1000 Get the Complete MaterialAbstractThe objectives of the study are to evaluate the effects of orally administered pawpaw, avocado leaves extract alone and a combination of both pawpaw and avocado leaves extract on the kidney integrity of guinea pigs. A total of twenty-four guinea pigs were divided into four groups containing six guinea pigs each. Group I, II, III and IV received 5ml/kg distilled water, pawpaw leaves extract, avocado leaves extracts and a combination of pawpaw and avocado leaves extract respectively. Some parameters were investigated at the end of the experiment. The result revealed a significant increase in the blood urea nitrogen, creatinine, sodium, bicarbonate and globulin in the avocado leaves extract treated guinea pigs (P0.05). On the other hand, the blood urea nitrogen (BUN), creatinine, sodium and chloride were reduced (P0.05) with an increase in bicarbonate in the pawpaw leaves extract treated guinea pigs. Also the blood creatinine, sodium and potassium were reduced (P0.05) in the group treated with a combination of pawpaw and avocado leaves extract. The histological examination of the kidney revealed a disruption in the kidney integrity caused by the extracts. This result indicates that both pawpaw and avocado leaves extracts may be nephotoxic. The toxicity observed in both extract could be dose-dependent....Preview Download Preview +Other Microbiology project topics and materials you might be interested in»Bacterial analysis of urine polluted environment in federal polytechnic Nekede, Owerri»Isolation and identification of microbes associated with spoilage bread»Microbiological quality of palm kernel fruits»Microbiological evaluation of home made grape juice»Therapeutic potential of Moringa Oleifera leaves»Antibacterial activity of honey on staphylococcus aureusescherichia coli and streptococcus pyogen isolated from wound»Bacteriological monitoring of abattoirs in Ehime Mbano in Imo state»Phytochemical screening and antimicrobial assessment of Spondias Mombin (Ijikara)»Proximate, selected vitamins, and minerals analysis of Moringa Oleifera»Biodeterioration of natural and artifical stone»Isolation and identification of bacterial aerosols bioaerosols dump sites in Yenagoa»The effect of crude avocado and pawpaw leaves extract on kidney function of guinea pigs»Microbial examination of raw meat obtained at main abattoir, Offa»Isolation and characterization of fungi associated with the spoilage of corn grown in farms in Rukpokwu community»Incidence of staphylococcus and salmonella species in Kunuaya retailed in Yenagoa