The effect of ethanolic leaves extract of Laportea Aestuans on the kidney function indices of Alloxan induced diabetic male albino Wistar rats Department: Biochemistry By: Wiseone Project ID: 5536 Rating: (3.3) votes: 6Rate this project12345 Price:₦3000 Get the Complete MaterialAbstractInvestigation of the effect of ethanolic leaves extracts of Laportea aestuans on the kidney function indices of alloxan induced diabetic male albino wistar rats was conducted using standard analytical methods. Twenty-five (25) male healthy albino Wistar rats weighing 137– 177g were randomly assigned to five (5) groups of five (5) animals each. Group 1 which was the control were sustained on normal feed and water only, group 2, 3, 4 and 5 were administered with 150mg/kg body weight of alloxan monohydrate intrapentoneally after overnight fast. Fasting blood glucose was conducted and animals with blood glucose of 200mg/dl and above were considered as diabetic. Group 3 was treated with 80mg//kg metformin, Group 4 and 5 were treated with 50 and 150mg/kg body weight. Treatments lasted for 21 days, all rats were allowed free access to rat chow at ad libitum. The results showed a significant (p 0.05) increase in urea, uric acid and creatinine concentration in the diabetic control when compared to the non-diabetic control. However, significant (p 0.05) reduction was observed in both metformin and extract treated groups when compared to the untreated groups. The results suggest reno-protective potential of the extract at the tested dosage....Preview Download Preview +Other Biochemistry project topics and materials you might be interested in»Phytochemical and nutritive composition of fluted pumpkin»Determination of ascorbic acid in selected fruits mango, orange and pineapple using spectro-photometric method»Comparative evaluation of heavy metal loads in some selected soft drinks in Owerri, Imo state»Antilipidemic effect of water (H2O) extract of desmodium velutinum leaves on albino Wistar rats»The effect of water extract of cola nitida pod on lipoprotein concentrations of albino Wistar rats»Preliminary investigation on effects of burantashi extract on lipoproteins of albino male and female whistar rats»The extraction of manganese (iv) ion from aqueous media using 1-phethyl-3-methyl pyrazolone-5»Nutritive value, anti-nutrient and mineral composition of cashew nut (Anacardium Occidentale)»Evaluation of the immunomodulatory effect of oral administration of the methanol extract of gongronema latifolium (utazi) in wistar albino rats»Comparative study on the free radical scavenging potential of turmeric and beetroot»Phytochemicals and minerals analysis of rosary pea (Abrus Precatorious leaves)»Determination of total petroleum hydrocarbons in Niger river»Qualitative phytochemical and gas chromatography mass spectrometry GCMS of Nhexane extracted leaves of sabicea calycina»Hydrogen peroxide scavenging activities and reducing power of various fruits juice in Yenagoa»Charges in the concentration of nitric oxide in the serum gills brain liver and kidney of clarias gariepinus exposed to glyphosatebased herbicide