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Kidney function status of Levonorgestrel wistar albino rat treated with Datura Stramonium methanol leaves extract

 Department: Biochemistry  
 By: usericon SIRJOSEPH  

 Project ID: 8440
   Rating:  (5.0) votes: 1
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   Price:₦4000
Abstract
The current study investigates the ameliorative effects of the leaf extract of Datura stramonium on 20 albino rats induced with levonorgestrel toxicity. Kidney biomarkers (Urea and creatinine) were assayed. The plant leaves extract was shown to increase the levels of Urea and creatinine decreased by levonorgestrel. The results showed that Urea and creatinine levels decreased from 200 ±0.01 and 40.80 ± 0.42, respectively. But upon treatments with 100mg/kg bw of Datura stramonium, creatinine increased (40.00 ± 0.20) and urea (1.99 ± 0.01) improved. A further increase in the concentration of the plant extract to 300mg/kg bw significantly (P= 0.05) elevated the levels of urea and creatinine, 1.99 ± 0.03 and 40.55 ± 0.31, respectively. ...
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