Formulation of ointment using Mitracarpus Scaber extract and its antifungal activity against clinical isolate Department: Pharmaceutical Technology By: Muhammnnad1 Project ID: 8443 Rating: (5.0) votes: 1Rate this project12345 Price:₦4000 Get the Complete MaterialAbstractThe study was aimed to formulate an ointment using mitracarpus scaber extract against clinical isolates of Candida albicans& Aspergillus niger. The phytochemical screening was conducted by the conventional method and the antifungal activity of the extract was determined by using the disc diffusion method. The preliminary phytochemical screening of the leaf extracts showed the presence of alkaloid, flavonoid, tannin, quinone, and phenol. However, saponin& anthraquinone was present in the aqueous extract but absent in the ethanol extract. Steroid is present only in the ethanol extract. The antifungal activity of the extract depends on its concentration and the types of isolates. Highest zone of inhibition is demonstrated by Candida, 20.00mm, while Aspergillus demonstrated low sensitivity, recording 9.00mm. The aqueous leaf extract was more active against the isolate,s producing an average zone of inhibition of 20.0 mm, while the ethanol extract produced 9.0mm. It is concluded that extracts of Mitracarpus scaber leaf possess antifungal agents. ...Preview Download Preview +Other Pharmaceutical Technology project topics and materials you might be interested in»Comparative analysis of the acidity of different brands of folic acid sold in Owerri»Spectroscopic analysis of the first eluate of Piper Guineense extract»Knowledge, attitude and practice of prescription of drugs among school of community health science College of Health Sciences and Technology, Tsafe, Zamfara state»Analysis of the impact of electronic prescribing on medication safety and efficiency»Phytochemical screening, proximate and elemental analysis of two varieties of bitter kola (Garcinia kola) seed sold in Mariri market, Kano state»Identification of phytochemicals responsible for anti-ulcer activity of acioa barteri using high performance liquid chromatography-diode array detector (HPLC-DAD)»Antimicrobial activity of Acioa Barteri and its synergestic effect with Darlium Guineense»Formulation of ointment using Mitracarpus Scaber extract and its antifungal activity against clinical isolate