Levonorgastrel induced toxicity and effects of Datura Stramonium leaves on some serum electrolytes Department: Biochemistry By: SIRJOSEPH Project ID: 8484 Rating: (5.0) votes: 1Rate this project12345 Price:₦4000 Get the Complete MaterialAbstractSerum electrolyte concentration is among the most commonly used laboratory tests for assessment of a patient’s clinical conditions and disease states, because electrolyte balance in the body is essential for the normal functioning of cells and organs. Datura stramonium has been a useful plant in the treatment of so many diseases, but there seems to exist very little research on this plant in the area of serum electrolytes. The current studies examined the effects of levonorgestrel on the serum electrolytes of 20 albino rats divided into five groups of four (n 4) and treated with 100, 200, and 300 mg/kg body weight of the methanol leaves extracts of Datura stramonium. The studies showed the lowering effects of Datura stramonium on serum electrolyte levels. The result showed that chloride ion (Cl-) levels were significantly (p< 0.05) decreased from 91.75 ± 3.12 in the control (group 1) to 69.46 ± 46.30 (group 2). Calcium, Ca+ levels were also observed to decrease in a similar manner. Ca+ levels decrease from 9.81 ± 0.50 to 7.58 ± 1.83. Upon treatment with 100mg/kg of the methanol leaves extract of Datura stramonium, calcium and chloride levels were significantly (p< 0.05) increased to 9.53 ± 1.68 and 93.99 ± 1.12, respectively. Slightly lower levels of both chloride and calcium (46.34 ± 53.51 and 9.13 ± 0.74) were noticed upon treatment with 200mg/kg of the methanol leaves extract. Amazingly, increasing the dosage of the leaves extract of Datura stramonium to 300mg/kg elevated the levels of chloride (92.45 ± 2.37) and calcium (9.70 ± 0.89). This suggests that higher doses of the methanol leaves extract of Datura stramonium will increase the levels of calcium and chloride. ...Preview Download Preview +Other Biochemistry project topics and materials you might be interested in»Phytochemical and nutritive composition of fluted pumpkin»Determination of ascorbic acid in selected fruits mango, orange and pineapple using spectro-photometric method»Comparative evaluation of heavy metal loads in some selected soft drinks in Owerri, Imo state»Preliminary investigation on effects of burantashi extract on lipoproteins of albino male and female whistar rats»Antilipidemic effect of water (H2O) extract of desmodium velutinum leaves on albino Wistar rats»The effect of water extract of cola nitida pod on lipoprotein concentrations of albino Wistar rats»Nutritive value, anti-nutrient and mineral composition of cashew nut (Anacardium Occidentale)»The extraction of manganese (iv) ion from aqueous media using 1-phethyl-3-methyl pyrazolone-5»Evaluation of the immunomodulatory effect of oral administration of the methanol extract of gongronema latifolium (utazi) in wistar albino rats»Comparative study on the free radical scavenging potential of turmeric and beetroot»Phytochemicals and minerals analysis of rosary pea (Abrus Precatorious leaves)»Determination of total petroleum hydrocarbons in Niger river»Qualitative phytochemical and gas chromatography mass spectrometry GCMS of Nhexane extracted leaves of sabicea calycina»Quality assessment of some selected sachet water sold in Bayelsa state»Hydrogen peroxide scavenging activities and reducing power of various fruits juice in Yenagoa