Phytochemical screening and antimicrobial activity of Jatropha Tanjorensis leave extract on some bacteria species Department: Microbiology By: Mhiztaslim Project ID: 8689 Rating: (3.3) votes: 6Rate this project12345 Price:₦4000 Get the Complete MaterialAbstractThe increasing emergence of multidrug-resistant (MDR) bacterial infections has intensified the global search for alternative antimicrobial agents, particularly from plant sources. This study investigates the phytochemical composition and antimicrobial activity of Jatropha tanjorensis leaf extracts against selected bacterial species. The plant, traditionally used in African ethnomedicine, was collected and processed to obtain both aqueous and ethanol extracts. Phytochemical screening revealed the presence of bioactive compounds such as alkaloids, saponins, tannins, flavonoids, and terpenoids, particularly more abundant in ethanol extracts, while aqueous extracts showed higher antimicrobial potency. Antibacterial activity was evaluated using disc diffusion, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) assays against Escherichia coli and Bacillus cereus. The aqueous extract demonstrated stronger antimicrobial activity than the ethanol extract, with larger zones of inhibition and lower MIC and MBC values. Bacillus cereus exhibited greater susceptibility than E. coli, suggesting enhanced efficacy against Gram-positive bacteria. The aqueous extract''s MIC ranged between 25–50 mg/mL, while its MBC values were between 50–75 mg/mL, indicating significant bacteriostatic and bactericidal properties. These findings validate the traditional use of J. tanjorensis leaves for treating bacterial infections and highlight its potential as a source of novel antimicrobial agents. The superior efficacy of aqueous extracts suggests that water is a more suitable solvent for extracting active compounds from the LEAVE. Further studies, including compound isolation, mechanism of action, toxicity profiling, and synergistic assessments with standard antibiotics, are recommended to support therapeutic development....Preview Download Preview +Other Microbiology project topics and materials you might be interested in»Isolation and identification of microbes associated with spoilage bread»Bacterial analysis of urine polluted environment in federal polytechnic Nekede, Owerri»Microbiological quality of palm kernel fruits»Microbiological evaluation of home made grape juice»Therapeutic potential of Moringa Oleifera leaves»Antibacterial activity of honey on staphylococcus aureusescherichia coli and streptococcus pyogen isolated from wound»Phytochemical screening and antimicrobial assessment of Spondias Mombin (Ijikara)»Bacteriological monitoring of abattoirs in Ehime Mbano in Imo state»Proximate, selected vitamins, and minerals analysis of Moringa Oleifera»Biodeterioration of natural and artifical stone»The effect of crude avocado and pawpaw leaves extract on kidney function of guinea pigs»Isolation and characterization of fungi associated with the spoilage of corn grown in farms in Rukpokwu community»Microbial examination of raw meat obtained at main abattoir, Offa»Isolation and identification of bacterial aerosols bioaerosols dump sites in Yenagoa»Incidence of staphylococcus and salmonella species in Kunuaya retailed in Yenagoa