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 Home»Microbiology» Seroprevalence of herpes simplex virus-1 among HIV positive patients attending HIV clinic at Federal Teaching Hospital Owerri

Seroprevalence of herpes simplex virus-1 among HIV positive patients attending HIV clinic at Federal Teaching Hospital Owerri

 Department: Microbiology  
 By: usericon samadchuks  

 Project ID: 9188
   Rating:  (5.0) votes: 1
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   Price:₦5000
Abstract
This study investigated the prevalence of herpes simplex virus type 1 (HSV-1) IgG antibodies among 125 HIV-positive patients attending a Federal Medical Centre in Owerri, Imo State, Nigeria. Serological testing using rapid HSV-1 IgG/IgM kits was done according to the kit manufacturer''s instructions. The test result revealed an overall HSV-1 IgG prevalence of 9.6%, significantly lower than global estimates (67%) but consistent with regional trends. Demographic analysis identified disparities: males exhibited higher seropositivity (15.4%) than females (7.0%), and the 40–49 years age group had the highest prevalence (12.5%). Occupation and marital status also influenced rates, with artisans (13.5%) and single individuals (12.5%) showing elevated risks, while married participants mirrored the overall prevalence (9.9%). Educational attainment showed no significant correlation. The findings suggest unique regional transmission patterns, potentially influenced by occupational exposures, marital stability, or diagnostic limitations. The study underscores the need for targeted screening, education, and integration of HSV-1 management into HIV care programs in Owerri. Recommendations include expanding epidemiological research, improving healthcare access, and addressing socioeconomic determinants of co-infection. This research contributes critical baseline data to inform public health strategies aimed at reducing HSV-1/HIV co-infection burdens in southeastern Nigeria....
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